Vitamin D is part of a group of fat-soluble vitamins which can be obtained from a few foods, sunlight and supplements. The main role of Vitamin D is to assist in the metabolism of Calcium and Phosphorus and also in mineralization of bones. Till now, different forms of Vitamin D have been discovered, namely Vitamin D1, D2, D3, D4 and D5 respectively.
Vitamin D Deficiency – Reduced dietary intake or inadequate exposure to sunlight can lead to a deficiency of Vitamin D in the human body. Some studies have defined deficiency as a serum 25-hydroxyvitamin D level of less than 20 ng per mL (50 nmol per L), and insufficiency is defined as a serum 25-hydroxyvitamin D level of 20 to 30 ng per mL (50 to 75 nmol per L). In case of insufficient Vitamin D levels, 25 hydroxy- cholecalciferol was brought to the kidney and thus the kidneys cannot respond naturally and they fail to connect with blood calcium. The levels of calcium phosphate crystals begin getting low and hence form less soft tissue in the body. Less calcium from the circulation also creates the bone releasing all available calcium, for normality of blood calcium level. The bones, as a result, turn soft and bendable. Calcium in the bone activates the action of the osteoclasts and works as a synthesizer to the bone as well. But Vitamin D deficiency can cause dematerialization the bone. Some significant symptoms are bone pain & soft bones, frequent bone fractures, bone deformities or growth retardation in children.